Analysis for N-nitrosodiethanolamine is complicated by the matrix and a clean-up technique with derivatization is typically required before quantitation of the analyte to achieve adequate sensitivity and selec- tivity. Ammonium sulfamate may be added to the sample to prevent the artifactual for- mation of N-nitrosamines.
Original papers to the analysis of such material are: (a) Reducing the sample amount to 1 or 0.5 g; (b) filtering the final concentrate through a filter syringe; (c) use of cation- and anion exchange columns for additional clean-up; (d) modification of gas chromatography conditions (e. g., lowering the programme start temperature); (e) capillary gas chromatography instead of packed columns.Analysis of nitrosamines in cosmetics KANE IKEDA and KENNETH G. MIGLIORESE, Helene Curtis, Incorporated, Chicago, IL 60639. Received September 17, 1990. Synopsis A review of the technology available for the analysis of trace levels of secondary N-nitroso compounds in cosmetics and cosmetic raw materials is presented. Included are discussions on detection limits for indi- vidual nitrosamine.Abstract This study sought to develop a novel method for the trace analysis of N -nitrosodiethanolamine (NDELA) in shampoos inspired by a Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) extraction, followed by an RP-HPLC method with a water-rich mobile phase.
Abstract. A simple, reproducible gas chromatography-thermal energy analyzer (g.c.-TEA) method has been developed for the analysis of N-nitrosodiethanolainlne.
Abstract N-nitrosodiethanolamine is believed to be a weakly carcinogenic chemical, and as it occurs widely--in consumer products for example--it may constitute a significant hazard to humans.
Total Number of Papers: 90 (Display Entries) (Entries Per Page) per page Page Control Page: of: Abbreviation: NDELA: Long Form: N-nitrosodiethanolamine: No. Year Title Co-occurring Abbreviation; 1: 2020: Role of various factors affecting the photochemical treatment of N-nitrosamines related to CO2 capture. NDEA, NMOR: 2: 2018: Expression of Genes Encoding for Xenobiotic Metabolism After.
N-Nitrosomorpholine (NMOR) and N-nitrosodiethanolamine (NDELA) were painted on the clipped upper dorsal skin of male F344 rats. NDELA was applied undiluted, dissolved in water, and dissolved in cutting oil; NMOR was applied dissolved in water and in ethyl acetate. Aqueous solutions of the nitrosamines were used for gavage. Rats were housed individually. Blood and urine samples were analyzed.
N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is an organic compound with the formula (CH 3) 2 NNO. It is one of the simplest members of a large class of N-nitrosamines.It is a volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in lab animals.
Abstract. Methods for the determination and confirmation of N-nitrosodiethanolamine (NDELA) in cosmetic products were developed. The NDELA fraction was isolate.
Application 1-Nitrosopyrrolidine can be used to study carcinogens and cancer. Metabolism of nitrosamines in vivo has been tested in rats.1-Nitrosopyrrolidine has been used in a study to assess nitric oxide and spontaneous motility in chick embryos.
N-nitrosodiethanolamine is believed to be a weakly carcinogenic chemical, and as it occurs widely--in consumer products for example--it may constitute a significant hazard to humans. However, the chemical evidence concerning the identity, purity and properties of N-nitrosodiethanolamine is incomplete, and this casts some doubt on the basis of the current interest in this substance. In the.
N-nitrosodiethanolamine (NDELA), a type of nitrosamine, is a possible human carcinogen that may form in cosmetic products. The aim of this study was to examine the formation and inhibition of.
Abstract. A simple and novel method based on high-performance liquid chromatography with dual-wavelength ultraviolet detection at 234 and 254 nm has been developed for the determination of underivatized N-nitrosodiethanolamine in coconut diethanolamide.The correlation coefficient obtained shows that the method is correct.
N-Nitrosodiethanolamine This substance was considered by previous working groups, in October 1977 ( IARC, 1978 ) and March 1987 ( IARC, 1987 ). Since that time, new data have become available, and these have been incorporated in the monograph and taken into consideration in the evaluation.
Typically, 1,4-dioxane and nitrosamines are analyzed in drinking water following separate extraction and analysis procedures, such as Methods 521 and 522. However, here we present a combined method that uses large volume splitless injection and GC-MS (SIM) to meet low part-per-trillion detection limits for these compounds in a fraction of the time required when running separate methods.
This International Standard defines validation criteria with which analytical results obtained from the analysis of cosmetic products should comply in order to give confidence in performance,. This document references: ISO 3696 - Water for Analytical Laboratory Use - Specification and Test Methods. Published by ISO on April 15, 1987. Scope and field of application This International Standard.
The carcinogenic nitrosamine, N-nitrosodiethanolamine (NDElA), was degraded in samples of sewage and two lake waters, and microorganisms were responsible for the transformation. However, the rate.